| Local intra-arterial fibrinolysis without arterial occlusion? | |
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MedLine Citation:
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PMID: 10450851 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Local intra-arterial fibrinolysis (LIF) is the best choice at present for treatment of acute vessel occlusion in the vertebrobasilar territory and also, in selected cases, in the carotid territory. In almost all cases angiography demonstrates the site of occlusion exactly and gives information about collateral circulation. Contrary to this common approach, we report five patients with severe acute thromboembolic stroke in whom angiography revealed no occlusion of relevant arteries or their main branches. Under the hypothesis of persisting occlusion of perforating arteries to the brain stem we performed LIF in patients with a clinical basilar artery syndrome. Outcome in all but one of them was good following LIF. The clinical details are described and possible reasons discussed. |
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Authors:
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M Schumacher; L Yin; J Klisch; A Hetzel |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Neuroradiology Volume: 41 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 1999 Jul |
Date Detail:
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Created Date: 1999-09-20 Completed Date: 1999-09-20 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: GERMANY |
Other Details:
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Languages: eng Pagination: 530-6 Citation Subset: IM |
Affiliation:
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Section of Neuroradiology, University Hospital, Freiburg, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cerebral Angiography Cerebrovascular Disorders / diagnosis, drug therapy* Female Fibrinolytic Agents / administration & dosage*, therapeutic use Humans Infusions, Intra-Arterial Magnetic Resonance Imaging Male Middle Aged Thrombolytic Therapy / methods* Tissue Plasminogen Activator / administration & dosage*, therapeutic use Tomography, X-Ray Computed Urokinase-Type Plasminogen Activator / administration & dosage*, therapeutic use Vertebrobasilar Insufficiency / diagnosis, drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.21.68/Tissue Plasminogen Activator; EC 3.4.21.73/Urokinase-Type Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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