Document Detail

Local incentive spirometry improves peak expiratory flow rate in teenage sickle cell anaemia patients: a randomized pilot trial.
MedLine Citation:
PMID:  22275916     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Efforts to promote better health of sickle cell anaemia (SCA) patients in low-income countries through the use of cheap and available alternatives are desirable.
OBJECTIVE: We investigated whether a locally designed incentive spirometry will improve peak expiratory flow rate (PEFR) of teenage SCA patients.
METHODS: Forty-nine SCA teenagers were randomized into either the SCA spirometry or the SCA control groups, which had 24 and 25 patients respectively. They were initially compared with 25 matched non-SCA teenagers. The SCA spirometry group went through a six-week, thrice-daily local incentive spirometry while the control did not go through the exercise.
RESULTS: The PEFR of the SCA spirometry group improved significantly (p = 0.001) between the third and sixth week (211.04 ± 55.67 to 292.08 ± 40.86 litres/min) unlike that of the SCA control group (p = 0.605). At six weeks, PEFR of the SCA spirometry group improved significantly (t=0.624, p=0.003) over that of the SCA control group. However, the improved PEFR of the SCA spirometry group did not match that of their non-SCA counterparts.
CONCLUSIONS: Locally designed incentive spirometry improved PEFR of the SCA teenagers significantly in six weeks of spirometry exercise. Routine improvement in PEFR of SCA patients with the aid of incentive spirometry should be encouraged to improve lung function.
A F Adeniyi; K S Saminu
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  African health sciences     Volume:  11     ISSN:  1729-0503     ISO Abbreviation:  Afr Health Sci     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2012-01-25     Completed Date:  2012-05-22     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101149451     Medline TA:  Afr Health Sci     Country:  Uganda    
Other Details:
Languages:  eng     Pagination:  303-8     Citation Subset:  IM    
Department of Physiotherapy, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Nigeria.
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MeSH Terms
Anemia, Sickle Cell / physiopathology,  therapy*
Lung / physiopathology
Peak Expiratory Flow Rate* / physiology
Respiratory Therapy / methods*
Spirometry* / methods
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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