Document Detail


Local excision and mucosal advancement for anorectal ulceration in patients infected with human immunodeficiency virus.
MedLine Citation:
PMID:  7648098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients infected with human immunodeficiency virus (HIV) no effective surgical procedure has been described for anorectal ulceration that is resistant to medical therapy. This study was designed to determine the effectiveness of surgical excision of anorectal ulcers, with or without mucosal advancement. The medical records of patients with HIV and anorectal pathology diagnosed between 1984 and 1994 were reviewed. Patients with anorectal ulcers were divided into group A which was treated only with excision and group B in which excision was combined with mucosal advancement. Surgical treatment was considered successful if relief of symptoms was achieved within 4 weeks of the operation. Excision of anorectal ulcers was successful in seven of 16 patients (44 per cent) in group A. Relief of symptoms was achieved in 12 of 13 patients (92 per cent) in group B when surgical excision was combined with mucosal advancement, which is significantly better than the results in group A (P = 0.02). This non-randomized study indicates that after unsuccessful medical treatment persistent symptomatic ulcers should be treated operatively by excision with mucosal advancement.
Authors:
E C Consten; J F Slors; S A Danner; G J Offerhaus; J F Bartelsman; J J Van Lanschot
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  82     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-09-26     Completed Date:  1995-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  891-4     Citation Subset:  AIM; IM; X    
Affiliation:
Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / complications
Adult
Cytomegalovirus Infections / complications
Fissure in Ano / etiology,  surgery*
HIV Infections / complications*
Humans
Intestinal Mucosa
Male
Middle Aged
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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