Document Detail


Local excision of carcinoma of the rectum for cure.
MedLine Citation:
PMID:  1598675     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During the past 10 years, we have treated 63 patients with invasive adenocarcinoma of the rectum by full-thickness local excision. Rigid criteria were employed in patient selection. None of the tumors was pedunculated or in situ carcinoma. Of the 63 lesions, 53 were confined to the bowel wall and constitute the basis for this report. Thirty-five lesions penetrated only the submucosa and 18 invaded the muscularis propria. Twenty-four patients underwent full-dose postoperative radiotherapy with minimal complications. Follow-up ranged from 12 to 130 months, with a median of 44 months. Four tumors recurred locally (8%). Of these, two patients apparently have been salvaged by reexcision. One patient died 32 months after abdominoperineal resection of brain metastases (without local tumor). One patient who did not receive close follow-up died of local recurrence. Seven have died of unrelated causes. The 5-year corrected disease-free survival is 90%. Local excision combined with radiotherapy for selected rectal cancers yields a high rate of cure with minimal morbidity and is now our preferred mode of treatment for all patients whose tumors meet our rigid criteria.
Authors:
H R Bailey; W V Huval; E Max; K W Smith; D R Butts; L F Zamora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  111     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-07-09     Completed Date:  1992-07-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  555-61     Citation Subset:  AIM; IM    
Affiliation:
Division of Colon and Rectal Surgery, University of Texas Medical School, Houston.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / pathology,  surgery*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Invasiveness
Rectal Neoplasms / pathology,  surgery*
Recurrence
Retrospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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