| Local airway heat and water vapour losses. | |
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MedLine Citation:
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PMID: 1852986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A previously developed time-dependent mathematical model of the heat and water vapour transport in the human respiratory tract for mouth breathing (Daviskas et al., J. Appl. Physiol. 69:362-372, 1990) was applied to calculate the local quantities of heat and water transfer. The results of the heat and water losses agreed with experimental data. The contribution of each airway to the conditioning of inspired air was found to depend on the inspired air conditions and the pattern of breathing as expected. The greater proportion of the total heat and water loss was calculated to occur within the upper airways. However, below the pharynx, the rate of water loss during hyperpnea was calculated at a much faster rate than in the resting state. The rate at which water is returned to the airways may not be adequate to keep the periciliary fluid isotonic. These findings support the proposal that the intrathoracic airways could become significantly dehydrated during hyperpnea. The use of calculated local heat and water transfer rates may help to predict the site of stimuli to exercise-induced asthma. |
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Authors:
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E Daviskas; I Gonda; S D Anderson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Respiration physiology Volume: 84 ISSN: 0034-5687 ISO Abbreviation: Respir Physiol Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-08-20 Completed Date: 1991-08-20 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0047142 Medline TA: Respir Physiol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 115-32 Citation Subset: IM; S |
Affiliation:
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Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asthma
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etiology Body Temperature / physiology* Body Water / physiology* Hot Temperature Humans Models, Biological Physical Exertion / physiology* Respiration / physiology* |
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