| Local steroid injection via the cricothyroid membrane in patients with a vocal nodule. | |
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MedLine Citation:
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PMID: 22006779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To analyze the usefulness and safety of a steroid injection into vocal nodules via the cricothyroid membrane. Local administration of steroid directly into the larynx has been reported in many laryngeal diseases with different methods. DESIGN: Prospective case series at an academic tertiary care hospital. PATIENTS: Eighty patients with vocal nodules were enrolled between December 2008 and May 2010. INTERVENTIONS: Triamcinolone acetonide was injected through the cricothyroid membrane with a transnasal flexible laryngoscope to patients in a sitting position. MAIN OUTCOME MEASURES: Vocal nodules were evaluated before and 2 and 4 weeks after the injection; improvement was assessed both objectively and subjectively. RESULTS: The nodules disappeared in 35 patients by the fourth week after the injection (44%), and 39 patients showed improvement (49%). Jitter, shimmer, maximum phonation time, and mean voice handicap index also improved significantly after the steroid injection (P < .05 for all). Six patients with voice-related occupations showed improvement at the second week (8%), but the nodules had recurred after 4 weeks. Four patients experienced mild vocal fold atrophy, and 2 patients showed a white plaque formation on the vocal fold that resolved spontaneously 1 to 2 months after the injection. CONCLUSIONS: A local steroid injection via the cricothyroid membrane is a useful and safe treatment option for vocal nodules. However, vocal nodules are caused mainly by excessive voice use; therefore, nodules can recur unless the voice use pattern changes. Further study of this treatment technique, including long-term follow-up, is needed. |
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Authors:
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Sang-Hyuk Lee; Jang-Ok Yeo; Jeong-Im Choi; Hee-Jin Jin; Jin-Pyeong Kim; Seung-Hoon Woo; Sung-Min Jin |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of otolaryngology--head & neck surgery Volume: 137 ISSN: 1538-361X ISO Abbreviation: Arch. Otolaryngol. Head Neck Surg. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: 2011-12-29 Revised Date: 2012-08-15 |
Medline Journal Info:
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Nlm Unique ID: 8603209 Medline TA: Arch Otolaryngol Head Neck Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1011-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyeong-dong, Jongno-gu, Seoul, South Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Glucocorticoids / administration & dosage* Humans Injections / methods* Laryngeal Diseases / drug therapy*, pathology Laryngeal Muscles* Male Middle Aged Prospective Studies Treatment Outcome Triamcinolone Acetonide / administration & dosage* Vocal Cords* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 76-25-5/Triamcinolone Acetonide |
| Comments/Corrections | |
Comment In:
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Arch Otolaryngol Head Neck Surg. 2012 Jun;138(6):608
[PMID:
22710522
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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