Document Detail


Liver virtual non-enhanced CT with dual-source, dual-energy CT: a preliminary study.
MedLine Citation:
PMID:  20393717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To compare virtual non-enhanced liver CT (VNCT) from dual-energy CT (DECT) with true non-enhanced liver CT (TNCT) in patients.
METHODS: A total of 102 patients underwent multi-phase abdominal CT. Liver arterial VNCT (VNCT(A)) and portovenous VNCT (VNCT(V)) images were derived from the arterial and portovenous DECT data. The mean CT number, signal to noise ratio (SNR), image quality, contrast to noise (CNR) of liver lesions, lesion detectability and radiation dose were compared.
RESULTS: There was no difference in mean CT numbers of all organs (all P>0.05). SNR on VNCT images was higher than that of TNCT (all P<0.001). Image quality of VNCT was diagnostic but lower than that of TNCT (P<0.001). VNCT(A) images were superior to VNCT(V) (P<0.001). VNCT(A) and VNCT(V) detected 78 (91%) and 70 (81%) of 86 hepatic focal lesions visualised on TNCT. There was no difference in the size, attenuation and CNR of focal hepatic lesions (all P>0.05), but SNR of the lesions on VNCT was higher than that on TNCT (P<0.001). Radiation dose of biphase DECT was lower than that of routine triphase CT (P<0.001).
CONCLUSION: VNCT(A) may potentially replace TNCT as part of a multi-phase liver imaging protocol with consequent saving in radiation dose.
Authors:
Long-Jiang Zhang; Jin Peng; Sheng-Yong Wu; Z Jane Wang; Xin-Sheng Wu; Chang-Sheng Zhou; Xue-Man Ji; Guang-Ming Lu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-13     Completed Date:  2011-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2257-64     Citation Subset:  IM    
Affiliation:
Department of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, 305 Zhongshan East Road, Xuanwu District, Nanjing, Jiangsu Province 210002, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Contrast Media
Female
Humans
Liver / radiography*
Liver Neoplasms / radiography*
Male
Middle Aged
Pilot Projects
Radiography, Dual-Energy Scanned Projection / methods*
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Young Adult
Chemical
Reg. No./Substance:
0/Contrast Media

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