| Liver units in three dimensions: I. Organization of argyrophilic connective tissue skeleton in porcine liver with particular reference to the "compound hepatic lobule". | |
| | |
MedLine Citation:
|
PMID: 1862757 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Liver units were investigated in pig livers by means of histologic serial tracing, physical model building, and computer-aided three-dimensional imaging. Observations of the argyrophilic connective tissue skeleton were based mainly on the celloidin-embedded serial sections treated with silver impregnation. The parenchymal mass that clothed the initial segments of hepatic venous radicles was demarcated by fibrous septa which formed isolable units with two basic patterns: the simple hepatic lobule (SHL) and the compound hepatic lobule (CHL). Both lobule types presented regular limiting structures circumscribing each unit. Three-dimensional studies revealed that 25% of the lobules in a section belonged to the SHL type and 75% to the CHL type, the latter being predominant among the surface lobules. When considered in only two dimensions, however, the SHL-like lobules constituted the majority. Polygonal analysis disclosed that the pentagonal lobule was the most typical, instead of the "hexagonal" or "classic" lobule. The CHLs represented a multiaxial unit containing a system of venous tributaries in accordance with intralobular septation, whereas the SHLs were found with one axial vessel having a dendritic tendency at the incipient end; some SHLs were drained eccentrically by separate vessels into a sublobular vein. It was observed that, in dividing CHLs, whereas particular sinosoids were transformed into portal twigs, other sinusoids were changed into central venous tributaries. Fibrous deposition occurred along the septal-line sinusoids, bringing into view the septum-initiating plane. Fibroconnective tissue was supplied from the portal area and central (sublobular) adventitia, where portal triad structures and adventitial arterioles, respectively, were included. The findings of the present study facilitate the understanding of several characters of the lobules that have been reported previously, or occasionally postulated, such as the portal-central bridging tendency, the intralobular arterioles or ductules, the translobular artery or portal vein, the "portal-portal" or "portal-central" anastomoses, and the apposition of pericentral zone close to periportal zone. Based on differences in argyrophilia of sinusoidal reticulum, in proportion of lobule types, and in vasculature, the anatomic heterogeneity of liver unit was demonstrable in zonality, regionality, and locality. |
| | |
Authors:
|
W Ekataksin; K Wake |
Related Documents
:
|
22409127 - Intra-arterial therapy for acute stroke: trials and tribulations. 1533247 - Course before and after treatment of a patient with budd-chiari syndrome monitored by i... 841037 - Hepatic occlusion venography with a balloon catheter in portal hypertension. 15654577 - Sinistral portal hypertension; imaging findings and endovascular therapy. 20467877 - Monitored anesthesia care with dexmedetomidine of a patient with severe pulmonary arter... 17433497 - Humming is as effective as valsalva's maneuver and trendelenburg's position for ultraso... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The American journal of anatomy Volume: 191 ISSN: 0002-9106 ISO Abbreviation: Am. J. Anat. Publication Date: 1991 Jun |
Date Detail:
|
Created Date: 1991-08-30 Completed Date: 1991-08-30 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0376312 Medline TA: Am J Anat Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 113-53 Citation Subset: IM |
Affiliation:
|
Department of Anatomy Division I, Faculty of Medicine, Tokyo Medical and Dental University, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Connective Tissue / anatomy & histology* Image Processing, Computer-Assisted Liver / anatomy & histology* Silver / diagnostic use* Swine / anatomy & histology* |
| Chemical | |
Reg. No./Substance:
|
7440-22-4/Silver |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mechanisms of oxidant-induced changes in erythrocytes.
Next Document: Distribution of five peptides, three general neuroendocrine markers, and two synaptic-vesicle-associ...