Document Detail


Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.
MedLine Citation:
PMID:  22278680     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: LPC markers correlate positively with severity of liver disease and short-term mortality in AH patients. This study suggests that LPC proliferation may be an important feature of AH pathophysiology.
Authors:
Pau Sancho-Bru; José Altamirano; Daniel Rodrigo-Torres; Mar Coll; Cristina Millán; Juan José Lozano; Rosa Miquel; Vicente Arroyo; Juan Caballería; Pere Ginès; Ramon Bataller
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-04-23
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  55     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-30     Completed Date:  2012-08-02     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1931-41     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
Affiliation:
Liver Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Spain. psancho@clinic.ub.es
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MeSH Terms
Descriptor/Qualifier:
Antigens, CD / analysis
Antigens, Neoplasm / analysis
Biological Markers
Cell Adhesion Molecules / analysis
Female
Glycoproteins / analysis
Hepatitis, Alcoholic / mortality*
Humans
Immunohistochemistry
Keratin-7 / analysis
Liver / pathology*
Male
Middle Aged
Peptides / analysis
Severity of Illness Index
Stem Cells / chemistry*
Chemical
Reg. No./Substance:
0/AC133 antigen; 0/Antigens, CD; 0/Antigens, Neoplasm; 0/Biological Markers; 0/Cell Adhesion Molecules; 0/EPCAM protein, human; 0/Glycoproteins; 0/KRT7 protein, human; 0/Keratin-7; 0/Peptides
Comments/Corrections
Comment In:
Hepatology. 2012 Nov;56(5):2010-1; author reply 2011   [PMID:  22605508 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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