Document Detail

Liver metastases from melanoma: detection with multiphasic contrast-enhanced CT.
MedLine Citation:
PMID:  10540646     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the clinical utility of multiphasic computed tomography (CT) of the liver in patients with metastatic melanoma. MATERIALS AND METHODS: Nonenhanced and biphasic hepatic CT examinations were performed in 28 patients with metastatic melanoma, and liver lesion conspicuity was graded. CT studies in 20 patients met the eligibility criteria, and 13 patients had liver lesions. RESULTS: A total of 57 liver lesions were seen on CT studies: 48 on hepatic arterial phase images, 49 on portal venous phase phase images, and 30 on delayed phase images. Of eight lesions overlooked on portal venous phase images, six were seen on nonenhanced images, and six were seen on arterial phase images. Twenty-eight lesions were graded as more conspicuous on portal venous phase images; 10 were graded as more conspicuous on arterial phase images. CONCLUSION: CT images obtained only during the portal venous phase would have resulted in eight (14%) overlooked lesions, which implies that more than one phase is needed for hepatic CT in patients with malignant melanoma. The combination of nonenhanced and portal venous phase CT was as effective as the combination of arterial and portal venous phase CT in these patients. Delayed phase CT did not improve lesion detection either alone or in combination with CT at other phases.
S P Blake; K Weisinger; M B Atkins; V Raptopoulos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  213     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-17     Completed Date:  1999-11-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  92-6     Citation Subset:  AIM; IM    
Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
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MeSH Terms
Contrast Media
Liver Neoplasms / radiography*,  secondary*
Melanoma / radiography*,  secondary*
Middle Aged
Sensitivity and Specificity
Skin Neoplasms / pathology*
Tomography, X-Ray Computed*
Triiodobenzoic Acids / diagnostic use
Reg. No./Substance:
0/Contrast Media; 0/Triiodobenzoic Acids; 87771-40-2/ioversol

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