| Liver lipids in Letterer-Siwe disease. | |
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MedLine Citation:
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PMID: 7449795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of Letterer-Siwe disease in a thirteen-month-old girl with markedly swollen gums, an enlarged liver, and seborrhoic skin eruptions is reported. She died from pyopneumothorax in spite of treatment with prednisolone and vinblastine. Analysis of hepatic lipids showed that there was remarkable increase in free fatty acid, which is not seen in normal human liver. Cholesterol ester was also accumulated in the liver tissue. However, the concentrations of phospholipids and glycerides were low and lysophospholipid was found. It is assumed that there was increased intracellular lipolysis in the proliferating reticuloendothelial cells. |
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Authors:
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H Miyata; R Murata; K Arita; K Yoshioka; T Yamamoto; H Suzuki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of pediatrics Volume: 135 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1980 Oct |
Date Detail:
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Created Date: 1981-03-24 Completed Date: 1981-03-24 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 91-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cholesterol Esters
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analysis Female Glycerides / analysis Histiocytosis, Langerhans-Cell / pathology* Humans Infant Lipids / analysis* Liver / analysis* Phospholipids / analysis Skin / pathology |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol Esters; 0/Glycerides; 0/Lipids; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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