| Liver in haemoglobin H disease. | |
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MedLine Citation:
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PMID: 5428045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There have been no published reports on the liver of patients with haemoglobin H disease. In 11 Chinese patients studied (six male and five female) with haemoglobin H disease hepatic function and histology were studied. Liver function was normal in all cases; however, the gamma globulin level was raised in four cases, the increase being mainly in IgG in all cases and IgA in six cases. Liver histology showed that one case had portal cirrhosis, six cases mild fibrosis, and four cases no fibrosis. Haemosiderosis, mainly in the parenchymal cells of the peripheral lobules, was mild in one case, moderate in four, and severe in the remainder of the cases. |
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Authors:
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C B Keng; T K Khoo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gut Volume: 11 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1970 May |
Date Detail:
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Created Date: 1970-08-27 Completed Date: 1970-08-27 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 423-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Bilirubin / blood Female Hemoglobinopathies / complications, pathology* Hemosiderosis / complications Humans Immunoglobulin G / analysis Immunoglobulin M / analysis Iron / analysis Liver / analysis, pathology* Liver Cirrhosis / complications, pathology Liver Function Tests Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin G; 0/Immunoglobulin M; 635-65-4/Bilirubin; 7439-89-6/Iron |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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