| Liver hemostasis using high-intensity focused ultrasound. | |
| | |
MedLine Citation:
|
PMID: 9428140 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Liver hemorrhage, the major cause of death in hepatic trauma, is notoriously difficult to control. We report on the use of high-intensity focused ultrasound (HIFU) to arrest the bleeding from incisions made in rabbit livers. A HIFU transducer, with a spherically curved aperture of 6.34 cm2 area, a focal length of 4 cm and a frequency of 3.3 MHz was used. In approximately 94% of the incisions, the hemorrhage was reduced to a slow oozing of blood in less than 2 min. The maximum temperature of liver tissue around the incision area, during HIFU application, was measured to be 86 degrees C. The mechanism of hemostasis, confirmed by histological examination, appears to be coagulative necrosis of a volume of liver tissue around the incision. We believe that acoustic hemostasis, with the unique characteristic of "volume cauterization," offers a novel method for the management of liver hemorrhage and, thus, has major clinical implications. |
| | |
Authors:
|
S Vaezy; R Martin; U Schmiedl; M Caps; S Taylor; K Beach; S Carter; P Kaczkowski; G Keilman; S Helton; W Chandler; P Mourad; M Rice; R Roy; L Crum |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Ultrasound in medicine & biology Volume: 23 ISSN: 0301-5629 ISO Abbreviation: Ultrasound Med Biol Publication Date: 1997 |
Date Detail:
|
Created Date: 1998-02-24 Completed Date: 1998-02-24 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1413-20 Citation Subset: IM |
Affiliation:
|
Bioengineering Laboratory, University of Washington, Seattle 98195, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bile Ducts / pathology Body Temperature Disease Models, Animal Hemorrhage / pathology, physiopathology, therapy* Hemostatic Techniques* Hepatic Artery / pathology Hepatic Veins / pathology Hot Temperature Liver / injuries Liver Diseases / pathology, physiopathology, therapy* Necrosis Rabbits Treatment Outcome Ultrasonic Therapy / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Remnants of Albunex nucleate acoustic cavitation.
Next Document: Ultrasound stimulation of rat testes damaged by busulfan.