| Liver functional volumetry for portal vein embolization using a newly developed (99m)Tc-galactosyl human serum albumin scintigraphy SPECT-computed tomography fusion system. | |
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MedLine Citation:
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PMID: 21523415 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: We developed a new combined (99m)Tc-galactosyl human serum albumin (GSA) scintigraphy single-photon emission computed tomography (SPECT)/CT system to evaluate the changes in functional liver volume with portal vein embolization (PVE). METHODS: We performed a prospective analysis of 25 patients treated with right PVE, and evaluated their functional liver volume perioperatively with a (99m)Tc-GSA scintigraphy SPECT-CT fusion system. The percentage of the non-tumorous remnant liver volume (%LV) and the percentage of functional remnant liver volume (%FLV) were estimated by using the following calculations: (future remnant volume - tumor volume)/(total liver volume - tumor volume) and functional future remnant liver volume/functional total liver volume, respectively. RESULTS: Before PVE, the correlation was strongly significant between %LV and %FLV of the non-embolized liver, and the data were nearly equal (the regression coefficient was 1.005, P < 0.0001). In contrast, after PVE, there was a significant correlation between %LV and %FLV (P < 0.0001), but the regression coefficient was 1.192. The % LV increased significantly, from 38.1 to 52.0%, and the increment was 13.9% (P < 0.0005). The %FLV was also increased significantly, from 36.6 to 58.0%, and the increment was 21.4% (P < 0.0001). The increment was 7.5% greater for the %FLV compared to that of the %LV (P < 0.001). CONCLUSIONS: The (99m)Tc-GSA scintigraphy SPECT-CT fusion system can estimate the correct functional liver volume and is useful in comparison with conventional CT volumetry. |
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Authors:
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Toru Beppu; Hiromitsu Hayashi; Hirohisa Okabe; Toshiro Masuda; Kosuke Mima; Ryu Otao; Akira Chikamoto; Koichi Doi; Takatoshi Ishiko; Hiroshi Takamori; Morikatsu Yoshida; Shinya Shiraishi; Yasuyuki Yamashita; Hideo Baba |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-27 |
Journal Detail:
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Title: Journal of gastroenterology Volume: - ISSN: 1435-5922 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9430794 Medline TA: J Gastroenterol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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