Document Detail


Liver function tests in patients receiving parenteral nutrition.
MedLine Citation:
PMID:  1901108     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 5-year prospective study was performed to monitor liver function tests (LFTs) in patients receiving total parenteral nutrition (TPN). A gradual and progressive rise was seen in the plasma concentration of bilirubin, aspartate transaminase, and alkaline phosphatase. The rate of rise was not increased in patients with LFT abnormalities before the start of TPN. Half of the patients had an episode of sepsis during TPN, but overall abnormal LFTs did not appear more common in these patients than in those without obvious sepsis. Patients with malignant disease, those requiring long-term TPN, and those requiring a nonstandard TPN regimen were more likely to develop raised LFTs.
Authors:
P J Clarke; M J Ball; M G Kettlewell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  15     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1991 Jan-Feb
Date Detail:
Created Date:  1991-05-01     Completed Date:  1991-05-01     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  54-9     Citation Subset:  IM    
Affiliation:
Nuffield Department of Surgery, John Radcliffe Hospital, Oxford, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Alkaline Phosphatase / blood
Aspartate Aminotransferases / blood
Bilirubin / blood
Female
Humans
Infection / physiopathology
Liver / physiology*
Liver Function Tests
Male
Middle Aged
Parenteral Nutrition, Total*
Prospective Studies
Chemical
Reg. No./Substance:
635-65-4/Bilirubin; EC 2.6.1.1/Aspartate Aminotransferases; EC 3.1.3.1/Alkaline Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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