Document Detail

Liver cysts in patients with autosomal dominant polycystic kidney disease.
MedLine Citation:
PMID:  7377224     Owner:  NLM     Status:  MEDLINE    
Liver cysts were found in 46 (29 per cent) of 158 patients over 10 years of age with documented autosomal dominant-type polycystic kidney disease (PKD) from 62 unrelated families. Hepatic cysts were not found in any patient at risk for PKD in whom renal cysts were not detected. The prevalence of liver cysts increased with advancing age and with declining rate of glomerular filtration. Results of clinical and laboratory studies indicate that polycystic liver disease in patients with autosomal dominant-type PKD is a benign condition, rarely, if ever, causing impaired liver function or portal hypertension.
J Milutinovic; P J Fialkow; T G Rudd; L Y Agodoa; L A Phillips; J I Bryant
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of medicine     Volume:  68     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  741-4     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Chromosome Aberrations
Chromosome Disorders
Cysts / etiology*,  genetics
Genes, Dominant
Liver Diseases / diagnosis,  etiology*,  genetics
Middle Aged
Polycystic Kidney Diseases / complications*,  diagnosis,  genetics

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