Document Detail


Liver Transplant From an ABO-Incompatible and Hepatitis C Antibody-Positive but an HCV-RNA Negative Living Donor in a Familial Amyloid Polyneuropathy Patient.
MedLine Citation:
PMID:  23194392     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Familial amyloid polyneuropathy is a rare, progressively disabling, and ultimately fatal inherited disease. Liver transplant is currently the only available treatment proven to halt the progression of familial amyloid polyneuropathy. We report a 31-year-old woman with familial amyloid polyneuropathy who received a living-donor liver transplant from her husband who was hepatitis C virus antibody-positive but HCV-RNA negative and ABO incompatible. Six years after the transplant, both donor and recipient have normal liver biochemistry results; no hepatitis C viral load has been detectable in the recipient. This is the first report of a living ABO-incompatible liver transplant from an anti-hepatitis C virus antibody-positive but an HCV-RNA negative donor. This experience suggests that the use of an anti-hepatitis C virus antibody-positive hepatic graft is possible in select circumstances.
Authors:
Takayuki Takeichi; Katsuhiro Asonuma; Hidekazu Yamamoto; Yuki Ohya; Kenji Okumura; Kwang-Jong Lee; Yukihiro Inomata
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-22
Journal Detail:
Title:  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation     Volume:  -     ISSN:  2146-8427     ISO Abbreviation:  Exp Clin Transplant     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101207333     Medline TA:  Exp Clin Transplant     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Transplantation and Pediatric Surgery, Postgraduate School of Medical Science, Kumamoto University Hospital, 1-1-1 Honjo, Kumamoto 860-8556, Japan.
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