Document Detail


Littoral cell angioma as a rare cause of splenomegaly.
MedLine Citation:
PMID:  11233776     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 58-year-old, otherwise healthy man presented with a sudden onset of watery diarrhea. A pseudomembranous colitis due to antibiotics was identified as the cause of the diarrhea. Enlargement of the spleen was detected during the evaluation. The enlarged, plump spleen (20 cm long, 7.1 cm wide) had multiple nodules that differed in size from 1 to 8 cm. Neither clinical nor other symptoms of an underlying malignant disease could be detected. Because the signs were of little diagnostic value we arranged a splenectomy, which showed a littoral cell angioma (LCA) to be the cause of splenomegaly. In addition to the case report, we have reviewed the literature, clinical manifestations, differential diagnosis, special gross and microscopic pathological findings, and the location of this benign vessel tumor in the pathology of the spleen.
Authors:
C Ziske; M Meybehm; T Sauerbruch; I G Schmidt-Wolf
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of hematology     Volume:  80     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-03-06     Completed Date:  2001-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  IM    
Affiliation:
Medizinische Klinik und Poliklinik I, Allgemeine Innere Medizin, Rheinische Friedrich-Wilhelms Universität, Bonn, Germany. ziske@uni-bonn.de
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MeSH Terms
Descriptor/Qualifier:
Hemangioma / complications*
Humans
Male
Middle Aged
Spleen / ultrasonography
Splenic Neoplasms / complications*
Splenomegaly / etiology*

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