Document Detail


Literature systematic review on the ophthalmological side effects of interferons.
MedLine Citation:
PMID:  22068863     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Interferons alpha and beta have been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complications of interferon therapy have been published. The objective of this study was to carry out a literature systematic review on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhages and retina ischemia.
Authors:
Yara Dadalti Fragoso; Marina Sanchez Sahm Paggiaro; Roberta Mastromauro; Gabriela da Silva Jacondino; Heather Marion Wilson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos brasileiros de oftalmologia     Volume:  74     ISSN:  1678-2925     ISO Abbreviation:  Arq Bras Oftalmol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-11-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400645     Medline TA:  Arq Bras Oftalmol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  306-10     Citation Subset:  IM    
Affiliation:
Department of Neurology, Universidade Metropolitana de Santos, Santos, SP, Brazil.
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