Document Detail

Listeriosis in human pregnancy: a systematic review.
MedLine Citation:
PMID:  21517700     Owner:  NLM     Status:  MEDLINE    
Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregnant women are at high risk for listeriosis, but symptoms are non-specific and diagnosis is difficult. The intracellular life-cycle of Listeria protects the bacterium from host innate and adaptive immune responses. Antibiotic treatment requires agents able to penetrate, distribute, and remain stable within host cells. Prolonged use of high-dose ampicillin can significantly improve neonatal outcome.
Ronald F Lamont; Jack Sobel; Shali Mazaki-Tovi; Juan Pedro Kusanovic; Edi Vaisbuch; Sun Kwon Kim; Niels Uldbjerg; Roberto Romero
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural; Review     Date:  2011-04-25
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  39     ISSN:  1619-3997     ISO Abbreviation:  J Perinat Med     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-10     Completed Date:  2011-08-25     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  227-36     Citation Subset:  IM    
Perinatology Research Branch, NICHD/NIH/DHHS, Wayne State University/Hutzel Women's Hospital, 3990 John R, Detroit, MI 48201, USA.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Food Microbiology
Foodborne Diseases / microbiology
Infant, Newborn
Infectious Disease Transmission, Vertical
Listeria monocytogenes / growth & development
Listeriosis* / diagnosis,  drug therapy,  prevention & control
Pregnancy Complications, Infectious* / diagnosis,  drug therapy,  prevention & control
Risk Factors
Grant Support
Reg. No./Substance:
0/Anti-Bacterial Agents
Comment In:
J Perinat Med. 2011 Nov;39(6):749-50   [PMID:  21834606 ]

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