Document Detail


Listeriolysin O secretion by Listeria monocytogenes in the presence of cysteine and sorbate.
MedLine Citation:
PMID:  7766229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of cysteine or cysteine-HCl and their combination with potassium sorbate on growth of Listeria monocytogenes and listeriolysin O (LLO) secretion, and on activation of LLO in the haemolysin assay system was studied. Both cysteine and cysteine-HCl (10 and 20 mmol l-1) enhanced LLO secretion in tryptic soy broth supplemented with yeast extract during 24 h incubation at 35 degrees C. While sorbate did not affect growth, it suppressed both LLO secretion and LLO activation by cysteine in the haemolysin activity assay. These findings provide further evidence that sulphydryl-containing enzymes are implicated in the mechanism of microbial inhibition of sorbate. Addition of sorbate to foods has the potential of inactivating listeriolysin and other thiol-dependent toxins.
Authors:
Y Kouassi; L A Shelef
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Letters in applied microbiology     Volume:  20     ISSN:  0266-8254     ISO Abbreviation:  Lett. Appl. Microbiol.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-06-13     Completed Date:  1995-06-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8510094     Medline TA:  Lett Appl Microbiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  B    
Affiliation:
Department of Nutrition and Food Science, Wayne State University, Detroit, MI, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacterial Toxins*
Cysteine / pharmacology*
Erythrocytes
Heat-Shock Proteins / drug effects,  secretion*
Hemolysin Proteins
Hemolysis / physiology
Listeria monocytogenes / drug effects*,  growth & development,  metabolism
Sheep
Sorbic Acid / pharmacology*
Chemical
Reg. No./Substance:
0/Bacterial Toxins; 0/Heat-Shock Proteins; 0/Hemolysin Proteins; 110-44-1/Sorbic Acid; 52-90-4/Cysteine; 72270-41-8/hlyA protein, Listeria monocytogenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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