Document Detail

Liquor bilirubin levels in normal pregnancy: a reassessment of early prediction of haemolytic disease.
MedLine Citation:
PMID:  4991485     Owner:  NLM     Status:  MEDLINE    
A comparison was made between chemically and spectrophotometrically determined concentrations of total bile pigment in the liquor amnii. For the period 16 to 26 weeks' gestation the upper limit of normal bile pigment to protein ratio was found to be 0.4. Levels above this would be required as an indication for intrauterine transfusion. In 110 cases of isoimmunization of pregnancy these criteria were applied in the diagnosis of severity of the condition. The ratio of the bile pigment to protein was used rather than a simple bile pigment measurement, and found to be valuable.Nevertheless, it is important to emphasize that fallacious high bilirubin readings may arise by using whatever method, particularly owing to bilirubin and other breakdown products of blood contaminating the liquor.
J Murray; D L Norrie; C R Ruthven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  4     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1970 Nov 
Date Detail:
Created Date:  1971-01-13     Completed Date:  1971-01-13     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  387-91     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis*
Bilirubin / analysis*
Blood Transfusion, Intrauterine
Erythroblastosis, Fetal / diagnosis*,  therapy
Gestational Age
Proteins / analysis
Rh-Hr Blood-Group System
Reg. No./Substance:
0/Proteins; 0/Rh-Hr Blood-Group System; 635-65-4/Bilirubin

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