Document Detail

Liquid ventilation.
MedLine Citation:
PMID:  16022146     Owner:  NLM     Status:  MEDLINE    
Respiratory diseases are the commonest cause of morbidity and mortality in newborn babies. During the past few years several new modalities of treatment like surfactant have been introduced. One of them, and probably the most fascinating, is of liquid ventilation. Partial liquid ventilation, on which much of the existing research has concentrated, requires partial filling of lungs with perfluorocarbons (PFC's) and ventilation with gas tidal volumes using a conventional mechanical ventilators. Various physico-chemical properties of PFC's make them the ideal media. It results in a dramatic improvement in lung compliance and oxygenation and decline in mean airway pressure and oxygen requirements. It shows further promise for lung lavaging procedures, pulmonary image enhancement, pulmonary administration of drugs and as a technique to increase functional residual capacity in lung hypoplasia syndromes. There are no long-term side effect reported.
Arvind Sehgal; Robert Guaran
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Indian journal of chest diseases & allied sciences     Volume:  47     ISSN:  0377-9343     ISO Abbreviation:  Indian J Chest Dis Allied Sci     Publication Date:    2005 Jul-Sep
Date Detail:
Created Date:  2005-07-18     Completed Date:  2005-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7612044     Medline TA:  Indian J Chest Dis Allied Sci     Country:  India    
Other Details:
Languages:  eng     Pagination:  187-92     Citation Subset:  IM    
Department of Neonatal Intensive Care, Liverpool Hospital, South Western Sydney Area Health Service, Sydney, New South Wales, Australia.
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MeSH Terms
Fluorocarbons / therapeutic use*
Infant, Newborn
Liquid Ventilation / methods*
Lung Compliance
Oxygen / blood
Respiratory Distress Syndrome, Newborn / therapy*
Reg. No./Substance:
0/Fluorocarbons; 7782-44-7/Oxygen

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