Document Detail

Liquid chromatography-mass spectrometry in food safety.
MedLine Citation:
PMID:  20392451     Owner:  NLM     Status:  MEDLINE    
The use of powerful mass spectrometric detectors in combination with liquid chromatography has played a vital role to solve many problems related to food safety. Since this technique is especially well suited for, but not restricted to the analysis of food contaminants within the food safety area, this review is focused on providing an insight into this field. The basic legislation in different parts of the world is discussed with a focus on the situation within the European Union (EU) and why it favors the use of liquid chromatography-mass spectrometry (LC-MS). Main attention in this review is on the achievements that have been possible because of the latest advances and novelties in mass spectrometry and how these progresses have influenced the best control of food allowing an increase in the food safety and quality standards. Emphasis is given to the potential and pitfalls of the different LC-MS approaches as well as in its possibilities to address current hot issues in food safety, such as the development of large-scale multi-residue methods and the identification of non-target and unknown compounds. Last but not least, future perspectives and potential directions are also outlined highlighting prospects and achievements.
Ashok Kumar Malik; Cristina Blasco; Yolanda Picó
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-03-18
Journal Detail:
Title:  Journal of chromatography. A     Volume:  1217     ISSN:  1873-3778     ISO Abbreviation:  J Chromatogr A     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9318488     Medline TA:  J Chromatogr A     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  4018-40     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier B.V. All rights reserved.
Laboratori de Nutrició i Bromatologia, Facultat de Farmàcia, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.
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MeSH Terms
Chromatography, Liquid / methods*
Consumer Product Safety / legislation & jurisprudence
Drug Residues / analysis
Food Analysis / legislation & jurisprudence,  methods*
Food Contamination / analysis*,  legislation & jurisprudence
Mass Spectrometry / methods*

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