| Liquid chromatographic-electrochemical detection screening procedure for six nitro-containing drugs in chicken tissues at low ppb level. | |
| | |
MedLine Citation:
|
PMID: 2759987 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A screening procedure is described for the detection of furazolidone, nitrofurazone, aklomide, zoalene, nitromide, and sulfanitran residues in a single extract of chicken liver, breast, or thigh muscle at the low ppb level. The method includes extraction of tissue with chloroformethyl acetate-dimethyl sulfoxide (50 + 50 + 0.8), adsorption on neutral alumina, and subsequent elution of the residues with pH 6.0 phosphate buffer-methanol (1 + 1). Eluants are separated on a 25 cm, 5 microns C18 column with pH 6.0 phosphate buffer-methanol (57.5 + 42.5) as mobile phase. The drugs are detected with an electrochemical detector in the reductive mode at -0.8 V. Mean recoveries from all tissues ranged from 76.5% for nitrofurazone to 97.1% for zoalene. |
| | |
Authors:
|
O W Parks |
Related Documents
:
|
11215997 - Detection and quantitation of morphine in fixed tissues and formalin solutions. 21156197 - Determination of ligustilide in the brains of freely moving rats using microdialysis co... 2897377 - Thin-layer chromatographic screening method for the tranquillizers azaperone, propiopro... 9061457 - High-performance liquid chromatographic separation of kyotorphin, a basic tyr-arg dipep... 16896247 - Spectrophotometric determination of arsenic in water samples based on micro particle fo... 18218187 - Determination of optical impurity of pregabalin by hplc with pre-column chiral derivati... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal - Association of Official Analytical Chemists Volume: 72 ISSN: 0004-5756 ISO Abbreviation: J Assoc Off Anal Chem Publication Date: 1989 Jul-Aug |
Date Detail:
|
Created Date: 1989-09-21 Completed Date: 1989-09-21 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 7505559 Medline TA: J Assoc Off Anal Chem Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 567-9 Citation Subset: IM |
Affiliation:
|
U.S. Department of Agriculture, Philadelphia, PA 19119. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Chickens Chromatography, Liquid Electrochemistry Meat / analysis* Nitro Compounds / analysis* |
| Chemical | |
Reg. No./Substance:
|
0/Nitro Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Simultaneous determination of oxytetracycline, tetracycline, and chlortetracycline in milk by liquid...
Next Document: Liquid chromatographic determination of chloramphenicol residues in meat: interlaboratory study.