| Liquid chromatographic analysis of vitamin K1 in milk-based infant formula with matrix solid-phase dispersion. | |
| | |
MedLine Citation:
|
PMID: 10513014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A liquid chromatographic method for vitamin K1 in milk-based infant formula is described. The vitamins are extracted from infant formula by matrix solid-phase dispersion and quantitated by reversed-phase chromatography with fluorescence detection. Vitamin K1 is converted to the fluorescent hydroquinone with a postcolumn zinc reductive reactor. The limit of detection is 12 pg, and the limit of quantitation is 38 pg on-column. Linear responses were obtained in the range 0.55-22.1 ng/ml (r2 = 0.9998). Recoveries of vitamin K1 from an analyte-fortified blank material for milk-based infant formula averaged 91.7% (n = 25). The method provides a rapid, specific, and easily controlled assay for vitamin K1 in fortified infant formula. |
| | |
Authors:
|
G W Chase; R R Eitenmiller; A R Long |
Related Documents
:
|
11433634 - Vitamin d deficiency and insufficiency in orthodox and non-orthodox jewish mothers in i... 1898584 - Vitamin b-6 metabolism in premature infants. 9681214 - Anaemia, vitamin e deficiency and failure to thrive in an infant. 9561624 - A comparative study of nutrition and health of mothers in japan and the philippines. 3660044 - Bishop score and labor duration: a new look. 3772834 - Mother's speech to their 1-year-old infants in home and laboratory settings. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of AOAC International Volume: 82 ISSN: 1060-3271 ISO Abbreviation: J AOAC Int Publication Date: 1999 Sep-Oct |
Date Detail:
|
Created Date: 1999-11-26 Completed Date: 1999-11-26 Revised Date: 2008-03-17 |
Medline Journal Info:
|
Nlm Unique ID: 9215446 Medline TA: J AOAC Int Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1140-5 Citation Subset: IM |
Affiliation:
|
U.S. Food and Drug Administration, Southeast Regional Laboratory, Atlanta, GA 30309, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Chromatography, Liquid* Infant Food / analysis* Linear Models Milk / chemistry* Sensitivity and Specificity Time Factors Vitamin K 1 / analysis* |
| Chemical | |
Reg. No./Substance:
|
84-80-0/Vitamin K 1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Determination of lipids in infant formula powder by direct extraction methylation of lipids and fatt...
Next Document: Determination of choline in infant formula by ion chromatography.