| Lipoprotein(a) levels in the nephrotic syndrome. | |
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MedLine Citation:
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PMID: 1477459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated serum lipoprotein(a) [Lp(a)] levels in 20 patients with the nephrotic syndrome. Lp(a) levels in the nephrotic syndrome patients were significantly higher than those in a control group (30.4 +/- 22.5 vs 10.4 +/- 17.7 mg/dl). Overall, the serum Lp(a) and lipid levels showed no relationship, but on an individual basis the serum Lp(a) level varied with the serum levels of total cholesterol and low density lipoprotein cholesterol in the nephrotic syndrome patients. Our findings suggest that a decrease in serum albumin led to increased hepatic Lp(a) synthesis. It is well known that thrombotic disease supervenes on hypercoagulability in the nephrotic syndrome, so the determination of Lp(a) levels in these patients may provide information which is useful for preventing thrombotic complications. |
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Authors:
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H Kanno; E Saito; T Fujioka; T Yasugi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 31 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1993-02-09 Completed Date: 1993-02-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 1004-8 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Cholesterol / blood Female Humans Lipoprotein(a) / blood* Lupus Nephritis / blood Male Middle Aged Nephrotic Syndrome / blood* Phospholipids / blood Serum Albumin / analysis Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Lipoprotein(a); 0/Phospholipids; 0/Serum Albumin; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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