Document Detail

Lipoprotein(a) levels in the nephrotic syndrome.
MedLine Citation:
PMID:  1477459     Owner:  NLM     Status:  MEDLINE    
We investigated serum lipoprotein(a) [Lp(a)] levels in 20 patients with the nephrotic syndrome. Lp(a) levels in the nephrotic syndrome patients were significantly higher than those in a control group (30.4 +/- 22.5 vs 10.4 +/- 17.7 mg/dl). Overall, the serum Lp(a) and lipid levels showed no relationship, but on an individual basis the serum Lp(a) level varied with the serum levels of total cholesterol and low density lipoprotein cholesterol in the nephrotic syndrome patients. Our findings suggest that a decrease in serum albumin led to increased hepatic Lp(a) synthesis. It is well known that thrombotic disease supervenes on hypercoagulability in the nephrotic syndrome, so the determination of Lp(a) levels in these patients may provide information which is useful for preventing thrombotic complications.
H Kanno; E Saito; T Fujioka; T Yasugi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  31     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1993-02-09     Completed Date:  1993-02-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1004-8     Citation Subset:  IM    
Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
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MeSH Terms
Cholesterol / blood
Lipoprotein(a) / blood*
Lupus Nephritis / blood
Middle Aged
Nephrotic Syndrome / blood*
Phospholipids / blood
Serum Albumin / analysis
Triglycerides / blood
Reg. No./Substance:
0/Lipoprotein(a); 0/Phospholipids; 0/Serum Albumin; 0/Triglycerides; 57-88-5/Cholesterol

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