| Lipoprotein (a) in young individuals as a marker of the presence of ischemic heart disease and the severity of coronary lesions. | |
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MedLine Citation:
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PMID: 16585023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to evaluate whether high levels and small isoforms of lipoprotein (a) [Lp(a)] are markers of risk of early myocardial infarction and markers of the severity of coronary atherosclerosis. Lp(a) levels and small apo(a) isoforms were higher in 222 patients than in 199 controls (p<0.001). In patients, Lp(a)> or =30 mg/dL was associated with the presence of coronary lesions (p=0.007) and the severity of coronary atherosclerosis (p=0.002). The present study suggests that Lp(a) levels and small isoforms are markers of early myocardial infarction and that Lp(a) levels > or =30 mg/dL are associated with severe patterns of coronary atherosclerosis. |
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Authors:
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Esther Zorio; Cristina Falco; Miguel A Arnau; Francisco España; Ana Osa; Luis A Ramon; Remedios Castello; Luis Almenar; Miguel A Palencia; Amparo Estelles |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Haematologica Volume: 91 ISSN: 1592-8721 ISO Abbreviation: Haematologica Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-04-04 Completed Date: 2006-06-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417435 Medline TA: Haematologica Country: Italy |
Other Details:
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Languages: eng Pagination: 562-5 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Research Centre, Hospital Universitario La Fe, Valencia, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biological Markers / blood Case-Control Studies Coronary Artery Disease Female Humans Lipoprotein(a) / blood* Male Middle Aged Myocardial Ischemia / diagnosis, pathology* Protein Isoforms Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Lipoprotein(a); 0/Protein Isoforms |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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