Document Detail

Lipoprotein (a) immunapheresis in the treatment of familial lipoprotein (a) hyperlipoproteinemia in a patient with coronary heart disease.
MedLine Citation:
PMID:  10227778     Owner:  NLM     Status:  MEDLINE    
This paper reports 2 years' experience with lipoprotein (a) (Lp[a]) immunapheresis which was successfully handled on a now 40-year-old patient with familial Lp(a) hyperlipoproteinemia inducing severe coronary heart disease with 2 myocardial infarctions and diffuse coronary sclerosis. Continued treatment by Lp(a) immunabsorption with specific sheep antibodies reduced stenosis in coronary vessels more than 50% and stopped the progression of coronary heart disease. A special apheresis technique and the results of continued absorption effects are described.
R Straube; H Kingreen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis     Volume:  2     ISSN:  1091-6660     ISO Abbreviation:  Ther Apher     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1999-05-19     Completed Date:  1999-05-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9706703     Medline TA:  Ther Apher     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
Department of Nephrology, District Hospital, Lüdenscheid, Germany.
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MeSH Terms
Blood Component Removal*
Coronary Angiography
Coronary Disease / etiology,  radiography,  therapy*
Coronary Vessels / pathology
Disease Progression
Follow-Up Studies
Hyperlipoproteinemias / complications,  genetics*,  therapy
Immunosorbents / therapeutic use
Lipoprotein(a) / blood*
Myocardial Infarction / etiology
Reg. No./Substance:
0/Immunosorbents; 0/Lipoprotein(a)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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