Document Detail

Lipoprotein (a): More than a bystander in the etiology of hypertension? A study on essential hypertensive patients not yet on treatment.
MedLine Citation:
PMID:  24475427     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: Hypertension (HTN) is a very common disorder with a substantial impact on public health because of its complications.
OBJECTIVES: To study the association of serum lipoprotein(a) [Lp(a)] elevation with essential hypertension (eHTN).
PATIENTS AND METHODS: This study was conducted on a group of essential hypertensive patients. Laboratory exams consisting of serum creatinine and Lp(a) were measured.
RESULTS: Ninety five essential hypertensive patients were enrolled to the study. Serum LP (a) in patients was 46.5±20. In patients an inverse correlation between serum Lp(a) andcreatinine clearance was seen (r = -0.175 p<0.05). There was a significant correlation between serum Lp(a) and age (r =0.191 p<0.05) or duration of HTN (known duration of hypertension period) (r =0.362 p<0.05).
CONCLUSIONS: Our data suggest that Lp(a) may be involved as a cofactor in essential hypertension, with a mechanism that remains to be elucidated.
Ali Ghorbani; Mahmoud Rafieian-Kopaei; Hamid Nasri
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Publication Detail:
Type:  Journal Article     Date:  2013-01-01
Journal Detail:
Title:  Journal of nephropathology     Volume:  2     ISSN:  2251-8363     ISO Abbreviation:  J Nephropathol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2014-01-29     Completed Date:  2014-01-29     Revised Date:  2014-02-03    
Medline Journal Info:
Nlm Unique ID:  101611182     Medline TA:  J Nephropathol     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  67-70     Citation Subset:  -    
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