| α-Lipoic Acid, Diabetic Neuropathy, and Nathan's Prophecy. | |
| | |
MedLine Citation:
|
PMID: 22253286 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Both oral and intravenous administration of alpha-lipoic acid (ALA) has been investigated as add-on treatment for diabetic peripheral neuropathy. The recent Neurological Assessment of Thioctic Acid in Diabetic Neuropathy (NATHAN) 1 trial has shown that 4-year oral ALA administration is of some value in achieving a clinically meaningful improvement and a slight delay in the progression of neuropathic deficits among patients with mild/moderate diabetic peripheral neuropathy. Despite these promising results, important questions remain to be answered, mainly appropriate patient selection and optimal treatment duration. Moreover, a cost-benefit analysis would be useful. |
| | |
Authors:
|
N Papanas; E Maltezos |
Related Documents
:
|
20007936 - Insulin gene mutations resulting in early-onset diabetes: marked differences in clinica... 18095216 - Endothelial no-synthase intron 4 polymorphism is associated with disturbed in vivo nitr... 16038876 - Serotonin transporter polymorphisms affect human blood glucose control. 21031056 - Null association between ace gene i/d polymorphism and diabetic nephropathy among multi... 10560676 - Inadequate suspension of neutral protamine hagendorn (nph) insulin in pens. 22049096 - Effects of pioglitazone and metformin on vascular endothelial function in patients with... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Angiology Volume: 63 ISSN: 1940-1574 ISO Abbreviation: Angiology Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
|
Languages: eng Pagination: 81-3 Citation Subset: IM |
Affiliation:
|
1 Outpatient Clinic of the Diabetic Foot, Second Department of Internal Medicine, Democritus University of Thrace, Greece. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The promoter activity of human Mfn2 depends on Sp1 in vascular smooth muscle cells.
Next Document: Generalization Procedures in Training Interventionists for Individuals With Developmental Disabiliti...