Document Detail

Lipoaugmentation of the vocal folds: a survey on alternative donor sites for graft harvesting.
MedLine Citation:
PMID:  18479890     Owner:  NLM     Status:  MEDLINE    
Lipoaugmentation is a treatment option for patients suffering from glottic insufficiency. Autologous fat is a nearly ideal material for vocal-fold augmentation from the view of biocompatibility and viscoelasticity, but there is still the problem of high graft resorption. As distribution and biological behavior of fatty tissue is very different in the human body, the aim of the study was to elucidate possible donor sites with respect to the quantity of harvested fat, the surgical accessibility to the region, the donor site morbidity and possibility of aesthetic defects and the quality of harvested tissue. Possible donor sites for harvesting were examined by magnetic resonance imaging in thirty-five patients with special emphasis to the buccal fat pad, the neck, the dorsolateral side of the proximal upper extremity, the subcutaneous layer of the abdominal wall, the superficial trochanteric region, the medial thigh, and the infrapatellar fat pad. Identified regions that failed to be chosen into consideration because of an elaborate surgical approach (superficial axillary's space, ischio-anal fossa, subcutaneous layer of buttock, popliteal fossa) were not taken into consideration. The mean volume of the buccal fat was 3.994 cm(3); the average thickness of the fat at the level of C7 was 1.721 cm, the mean value in the upper extremities was 1.913 cm laterally and 1.275 cm dorsally. The subcutaneous fat of the abdominal wall was divided into a superficial compartment (mean: 1.527 cm) and a deep one (average: 3.545 cm). In the superficial trochanteric region, the mean thickness was 2.536 cm, in the medial thigh 2.127 cm; the mean volume of the infrapatellar fat pad was 20.198 cm(3). All regions of interest showed reproducible and sufficient amounts of harvestable tissue, we found significant intersexual differences in dorsolateral side of the upper arm, subcutaneous layer of the abdominal wall and superficial trochanteric region. When harvesting subcutaneous tissue of the abdominal wall, grafts of the deep layer should be preferred, in the upper extremity the deep, muscle-neighbored parts. An alternative method is the surgically accessible fat of the neck. Solid fat pads could be harvested from the buccal region or the infrapatellar fat.
Peter Michael Prodinger; Gunther Windisch; Georg Philipp Hammer; Friedrich Anderhuber; Gerhard Friedrich
Publication Detail:
Type:  Journal Article     Date:  2008-05-14
Journal Detail:
Title:  Journal of voice : official journal of the Voice Foundation     Volume:  23     ISSN:  1873-4588     ISO Abbreviation:  J Voice     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-31     Completed Date:  2009-10-30     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8712262     Medline TA:  J Voice     Country:  United States    
Other Details:
Languages:  eng     Pagination:  625-30     Citation Subset:  IM    
Ear, Nose and Throat University-Hospital Department of Phoniatrics, Speech and Swallowing, Medical University Graz, 8010 Graz, Austria.
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MeSH Terms
Adipose Tissue, White / anatomy & histology,  surgery,  transplantation*
Aged, 80 and over
Laryngeal Diseases / surgery*
Magnetic Resonance Imaging
Middle Aged
Organ Size
Sex Characteristics
Subcutaneous Fat / anatomy & histology,  surgery,  transplantation
Tissue Transplantation / methods
Vocal Cords / surgery*
Young Adult

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