| Lipoadenoma of the parotid gland with probable striated duct differentiation. | |
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MedLine Citation:
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PMID: 9071732 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report an example of lipoadenoma of the parotid gland, a previously undescribed tumor of the salivary gland. It is a well-circumscribed tumor comprising an intimate admixture of mature fat cells and branching narrow tubules. The tubules were elongated and had small or absent lumina, resulting in a remarkable Sertoliform pattern. They were lined by columnar cells, which were supported by a basal cell layer. The latter cells lacked evidence of myoepithelial differentiation but were best highlighted by immunostaining for high molecular-weight cytokeratin (34 beta E12). Comparison with the normal salivary gland components showed the greatest homology of the neoplastic tubules with the striated duct, which normally has an incomplete basal cell layer. The latter phenomenon is under-recognized, with some current textbooks still describing the presence of a single cell type only in the striated duct of the salivary gland. |
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Authors:
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K C Yau; W Y Tsang; J K Chan |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Volume: 10 ISSN: 0893-3952 ISO Abbreviation: Mod. Pathol. Publication Date: 1997 Mar |
Date Detail:
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Created Date: 1997-05-13 Completed Date: 1997-05-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8806605 Medline TA: Mod Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 242-6 Citation Subset: IM |
Affiliation:
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Department of Pathology, Kowloon Hospital, Hong Kong. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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metabolism,
pathology*,
ultrastructure Adult Humans Immunohistochemistry Keratins / metabolism Male Parotid Neoplasms / metabolism, pathology*, ultrastructure |
| Chemical | |
Reg. No./Substance:
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68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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