| Lipids as modulators of bone remodelling. | |
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MedLine Citation:
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PMID: 11224653 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bone remodelling processes are regulated by systemic hormones and a multitude of local and systemic factors, including prostaglandins, cytokines, and growth factors. Dietary fatty acids and their derivatives (eicosanoids) have been a recent focus of investigation on bone and cartilage metabolism. Specific fatty acids are recognized modulators of eicosanoid biosynthesis, signal transduction, and gene expression. The actions of polyunsaturated fatty acids have not been extensively examined in the skeletal system. Promising research on fatty acids and bone remodelling should evaluate the potential effects on pathways for osteoclastogenesis and osteoblastogenesis. |
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Authors:
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B A Watkins; Y Li; M F Seifert |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in clinical nutrition and metabolic care Volume: 4 ISSN: 1363-1950 ISO Abbreviation: Curr Opin Clin Nutr Metab Care Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-03-06 Completed Date: 2001-07-26 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9804399 Medline TA: Curr Opin Clin Nutr Metab Care Country: England |
Other Details:
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Languages: eng Pagination: 105-10 Citation Subset: IM |
Affiliation:
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Department of Food Science, Lipid Chemistry and Molecular Biology Laboratory, Purdue University, West Lafayette, Indiana 47907, USA. watkins@foodsci.purdue.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone Remodeling* Bone and Bones / metabolism* Dietary Fats Fatty Acids, Unsaturated / administration & dosage*, metabolism Humans Lipid Metabolism* Osteoporosis / prevention & control Rats Risk Factors Signal Transduction |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Fatty Acids, Unsaturated |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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