Document Detail


Lipids as conductors in the orchestra of life.
MedLine Citation:
PMID:  22312416     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a lipid that is both composer and conductor, where in addition to its role as biosynthetic precursor (composer) it is also a potent signaling molecule (conductor) that integrates membrane biogenesis with nutrient sensing and cell growth. This article discusses recent advances in yeast that give praise for phosphatidic acid as one of life's conductors.
Authors:
Christopher J R Loewen
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Publication Detail:
Type:  Journal Article     Date:  2012-02-01
Journal Detail:
Title:  F1000 biology reports     Volume:  4     ISSN:  1757-594X     ISO Abbreviation:  F1000 Biol Rep     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101506835     Medline TA:  F1000 Biol Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  4     Citation Subset:  -    
Affiliation:
Department of Cellular and Physiological Sciences, Life Sciences Institute, The University of British Columbia 2350 Health Sciences Mall, Vancouver, British Columbia, Canada, V6T 1Z3.
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