| Lipidomics of host-pathogen interactions. | |
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MedLine Citation:
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PMID: 16859687 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The cell biology of intracellular pathogens (viruses, bacteria, eukaryotic parasites) has provided us with molecular information of host-pathogen interactions. As a result it is becoming increasingly evident that lipids play important roles at various stages of host-pathogen interactions. They act in first line recognition and host cell signaling during pathogen docking, invasion and intracellular trafficking. Lipid metabolism is a housekeeping function in energy homeostasis and biomembrane synthesis during pathogen replication and persistence. Lipids of enormous chemical diversity play roles as immunomodulatory factors. Thus, novel biochemical analytics in combination with cell and molecular biology are a promising recipe for dissecting the roles of lipids in host-pathogen interactions. |
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Authors:
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Markus R Wenk |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2006-07-13 |
Journal Detail:
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Title: FEBS letters Volume: 580 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 2006 Oct |
Date Detail:
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Created Date: 2006-10-03 Completed Date: 2006-11-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: Netherlands |
Other Details:
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Languages: eng Pagination: 5541-51 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, National University of Singapore, Yong Loo Lin School of Medicine, 8 Medical Drive, Block MD7, Singapore 117597, Singapore. bchmrw@nus.edu.sg |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Disease* Host-Parasite Interactions Humans Lipid Metabolism* Membrane Fusion Microarray Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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