| Lipid transport, dietary fats, and endogenous lipid synthesis: hypotheses on saturation and competition processes. | |
MedLine Citation:
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PMID: 16859175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma lipid concentrations are the net result of the balance between two opposite processes: the loading, i.e. the entry of new lipids into the plasma compartment through the ingestion (diet) and/or endogenous synthesis, and the unloading, i.e. energy utilization, incorporation into cell membranes, and storage. Even though many fatty acids are thought to be synthesized in the body, it appears as nearly all circulating fatty acids are, in fact, derived from the diet. In view of the wide dietary availabilty of such nutrients, the need to conserve energy likely minimizes endogenous synthesis. Consequently, the possibility exists to alter circulating the profile of fatty acids, including the "non essential" ones by dietary manipulations. In turn, a theory on the dietary vs endogenous contribution to circulating fatty acids, including those known as non-essential, is discussed based on critical interpretation of original data. |
Authors:
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Francesco Visioli; Michael A Crawford; Stephen Cunnane; Patrizia Rise; Claudio Galli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nutrition and health Volume: 18 ISSN: 0260-1060 ISO Abbreviation: Nutr Health Publication Date: 2006 |
Date Detail:
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Created Date: 2006-07-24 Completed Date: 2006-09-07 Revised Date: 2012-02-23 |
Medline Journal Info:
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Nlm Unique ID: 8306569 Medline TA: Nutr Health Country: England |
Other Details:
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Languages: eng Pagination: 127-32 Citation Subset: IM |
Affiliation:
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University of Milan, Department of Pharmacological Sciences, Italy, francesco.visioli@unimi.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Chemical Analysis Chromatography, Gas / methods Dietary Fats / administration & dosage*, metabolism Energy Metabolism / physiology* Fatty Acids / analysis*, chemistry Female Humans Lipid Metabolism / drug effects, physiology* Lipogenesis / drug effects, physiology* Lipolysis / drug effects, physiology* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Fatty Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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