Document Detail

Lipid oxidation according to intensity and exercise duration in overweight men and women.
MedLine Citation:
PMID:  17890494     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our objective was to compare the effect of different exercise intensities on lipid oxidation in overweight men and women. RESEARCH METHODS AND PROCEDURES: Nine young, healthy, overweight men and women were studied (age, 31.4 +/- 2.3 and 26.7 +/- 2.1 years; BMI, 27.9 +/- 0.4 and 27.2 +/- 0.5; for men and women, respectively). On one study day, the subjects first performed 30 minutes of cycling exercise at 30% of their maximal oxygen uptake (Vo(2max); E1 session), followed by 30 minutes of exercise at 50% Vo(2max) (E2 session). On a second study day, a similar E1 session was followed by 30 minutes of exercise at 70% Vo(2max) (E3 session). From the gas exchange measurements, the respiratory exchange ratio (RER) and the fat oxidation rate (FOR) were calculated. Plasma concentrations of glycerol and non-esterified fatty acids (NEFAs) were assayed. RESULTS: RER was significantly lower for women during only the E1 session. For both sexes, RER decreased over time during the E2 and E3 sessions. During the E1 session, the FOR per kilogram of lean mass (LM) was higher among women, and it did not change over time despite an increase in plasma NEFAs. FOR per kilogram of LM was higher during the E2 exercise for both sexes. During E2 and E3 sessions, as the exercise time was prolonged, the FOR/kg LM increased simultaneously with the increase in the plasma glycerol. DISCUSSION: Lipid oxidation during exercise is optimized for moderate and lengthy exercise. The enhancement of lipid oxidation occurring over time during moderate- and high-intensity exercises could be, in part, linked to the improvement of lipid mobilization. This fact is discussed to shed light on exercise modalities as a tool for the management of overweight.
Fabien Pillard; Cédric Moro; Isabelle Harant; Eric Garrigue; Max Lafontan; Michel Berlan; François Crampes; Isabelle de Glisezinski; Daniel Rivière
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  15     ISSN:  1930-7381     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-24     Completed Date:  2008-01-10     Revised Date:  2008-01-21    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2256-62     Citation Subset:  IM    
Service d'Exploration de la Fonction Respiratoire et d'Exploration Fonctionnelle en Médecine du Sport, Hôpital Larrey, TSA 30030, 31059 Toulouse cedex 9, France.
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MeSH Terms
Anthropometry / methods
Body Mass Index
Glycerol / metabolism
Lipid Metabolism
Lipids / chemistry*
Overweight / diagnosis*,  metabolism*
Oxygen / metabolism*
Oxygen Consumption
Sex Factors
Time Factors
Reg. No./Substance:
0/Lipids; 56-81-5/Glycerol; 7782-44-7/Oxygen

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