Document Detail


Lipid metabolism of Borrelia hermsi.
MedLine Citation:
PMID:  669794     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The synthesis of complex lipids by Borrelia hermsi while growing in Kelly medium was investigated by labeling cultures with D-[14C]glucose or [14C]palmitic acid. Labeled glucose was incorporated into phosphatidyl choline, phosphatidyl glycerol, monogalactosyl diglyceride, cholesterol glucoside, and acylated cholesteryl glucoside. The fatty acid composition reflected that of the medium suggesting that this spirochete directly incorporates acyl chains unaltered from its external milieu. Furthermore, the distribution of labeled carbon between acyl groups (lipid-soluble) and water-soluble moieties indicates that there is no metabolic exchange between these two pools. The relationship of B. hermsi to other spirochetes is discussed in terms of lipid metabolism as a generic characteristic.
Authors:
B P Livermore; R F Bey; R C Johnson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Infection and immunity     Volume:  20     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-09-29     Completed Date:  1978-09-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-20     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Borrelia / metabolism*
Chromatography, Gas
Chromatography, Paper
Chromatography, Thin Layer
Culture Media
Fatty Acids / analysis
Glucose / metabolism
Lipid Metabolism*
Lipids / analysis
Palmitic Acids / metabolism
Chemical
Reg. No./Substance:
0/Culture Media; 0/Fatty Acids; 0/Lipids; 0/Palmitic Acids; 50-99-7/Glucose
Comments/Corrections

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