| Lipid lowering therapy leads to a reduction in sodium-lithium countertransport activity. | |
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MedLine Citation:
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PMID: 1854357 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Erythrocyte sodium-lithium countertransport (SLC) was measured in 17 patients with either combined hyperlipidaemia or hypercholesterolaemia before and after lipid lowering therapy. Before treatment SLC related to the serum triglyceride level and was increased in combined hyperlipidaemia. After treatment the SLC had returned to normal and the change in SLC was related to the change in serum triglyceride levels. Raised SLC is associated with essential hypertension but is not related to blood pressure. Therefore, the association of raised SLC with hyperlipidaemia and essential hypertension appears to have different underlying mechanisms. |
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Authors:
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S J Carr; T H Thomas; M F Laker; R Wilkinson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Atherosclerosis Volume: 87 ISSN: 0021-9150 ISO Abbreviation: Atherosclerosis Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-08-16 Completed Date: 1991-08-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 103-8 Citation Subset: IM |
Affiliation:
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Department of Medicine and Nephrology, Freeman Hospital, Newcastle upon Tyne, U.K. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biological Transport, Active Cholesterol / blood Erythrocytes / metabolism Female Humans Hyperlipidemias / blood, therapy* Lipids / blood* Lithium / blood* Male Middle Aged Sodium / blood* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Lipids; 0/Triglycerides; 57-88-5/Cholesterol; 7439-93-2/Lithium; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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