| Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae L. | |
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MedLine Citation:
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PMID: 16557611 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The lipid lowering activity of chitosan associated with Aloe vera L. or hydrosoluble chitosan with Brassica olearaceae L. has been studied in rats. In this study, rats were submitted to different treatments with hydrosoluble chitosan alone (4% diet), hydrosoluble chitosan associated with Aloe vera L. or hydrosoluble chitosan with Brassica olearaceae L. (1:4, 4% diet) for 35 days, to identify the formula with the highest hypolipaemic potential. The results showed that all treatments reduced blood lipid levels but that hydrosoluble chitosan associated with Brassica olearaceae L. proved most efficient, because it decreased the levels of total cholesterol, LDL-cholesterol, VLDL-cholesterol and triglycerides in blood serum. The overall results suggest that the hydrosoluble chitosan/Brassica olearaceae L. association is a therapeutic alternative for hyperlipidaemia, and in this way may contribute to the prevention of atherogenic processes. |
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Authors:
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R Geremias; R C Pedrosa; C Locatelli; V T de Fávere; R Coury-Pedrosa; M C M Laranjeira |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 20 ISSN: 0951-418X ISO Abbreviation: Phytother Res Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-03-30 Completed Date: 2006-06-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 288-93 Citation Subset: IM |
Copyright Information:
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Copyright 2006 John Wiley & Sons, Ltd. |
Affiliation:
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Pharmacy Department, Extremo Sul Catarinense University, Criciúma, Santa Catarina, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aloe* Animals Antilipemic Agents / administration & dosage*, adverse effects Blood Glucose / metabolism Brassica* Chitosan / administration & dosage*, adverse effects Cholesterol / blood Drug Combinations Drug Synergism Male Plant Extracts / administration & dosage*, adverse effects Rats Rats, Wistar Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents; 0/Blood Glucose; 0/Drug Combinations; 0/Plant Extracts; 0/Triglycerides; 57-88-5/Cholesterol; 9012-76-4/Chitosan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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