| Lipid composition of spermatozoa in normozoospermic and asthenozoospermic males. | |
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MedLine Citation:
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PMID: 17693070 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Lipids play an important role in the structural and functional activity of spermatozoa. We investigated the phospholipids composition and fatty acid-bound phospholipid of spermatozoa from asthenozoospermic and normozoospermic men. PATIENTS AND METHODS: Semen samples were analyzed in 15 asthenozoospermic and eight normozoospermic subjects and the sperm phospholipids and fatty acids were determined using high performance thin layer chromatography and gas chromatography, respectively. RESULTS: The most abundant (mean+/-SE) phospholipids in normozoospermic and asthenozoospermic samples were phosphatidylethanolamine (70.9+/-11.5 and 44.2+/-8.5 nmol/10(8) spermatozoa, respectively) and phosphatidylcholine (58.6+/-9.5 and 34.6+/-3.2 nmol/10(8) spermatozoa, respectively). Compared to normozoospermic samples, asthenozoospermic samples showed lower levels of polyunsaturated fatty acids (PUFA; p<0.01) and higher levels of saturated fatty acids (SFA; p<0.05). DISCUSSION: Changes in content of phospholipids and its fatty acid composition of spermatozoa may be related to infertility in asthenozoospermic males. |
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Authors:
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Heidar Tavilani; Mahmoud Doosti; Issa Nourmohammadi; Hossein Mahjub; Asad Vaisiraygani; Saeedeh Salimi; Seyed Mohammad Hosseinipanah |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2007-08-10 |
Journal Detail:
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Title: Prostaglandins, leukotrienes, and essential fatty acids Volume: 77 ISSN: 0952-3278 ISO Abbreviation: Prostaglandins Leukot. Essent. Fatty Acids Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-08-20 Completed Date: 2008-01-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8802730 Medline TA: Prostaglandins Leukot Essent Fatty Acids Country: Scotland |
Other Details:
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Languages: eng Pagination: 45-50 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, School of Medicine, Hamadan University of Medical Science, Hamadan, Iran. tavilani@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asthenozoospermia / metabolism* Chromatography, Gas Chromatography, Thin Layer Fatty Acids / analysis*, metabolism Humans Male Phospholipids / chemistry* Sperm Motility Spermatozoa / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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