Document Detail


Lipid compartmentalization in erythrocytes parasitized by Plasmodium spp.
MedLine Citation:
PMID:  15463520     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Although reasonably well protected from the host immune system by the erythrocyte membrane, the intraerythrocytic malaria parasite has to make that membrane compatible with its own requirements for development and multiplication. The development of Plasmodium spp brings about major changes in the lipid composition of the host cell membrane, as well as in its physical properties. The parasite itself has a lipid composition that differs from that of the host cell and an intense lipid trafficking seems to occur between intracellular parasite and host cell membrane. Here, Ana Paula Simões, Ben Roelofsen and Jos Op den Kamp discuss how, despite serious methodological limitations and the existence of some conflicting results, an overall picture of lipid compartmentalization within the parasitized erythrocyte is perceived.
Authors:
A P Simões; B Roelofsen; J A Op den Kamp
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Parasitology today (Personal ed.)     Volume:  8     ISSN:  0169-4758     ISO Abbreviation:  Parasitol. Today (Regul. Ed.)     Publication Date:  1992 Jan 
Date Detail:
Created Date:  2004-10-06     Completed Date:  2005-04-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8605563     Medline TA:  Parasitol Today     Country:  England    
Other Details:
Languages:  eng     Pagination:  18-21     Citation Subset:  -    
Affiliation:
Centre for Biomembranes and Lipid Enzymology, University of Utrecht, PO Box 80054, 3508 TB, Utrecht, The Netherlands.
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Comments/Corrections
Comment In:
Parasitol Today. 1995 Aug;11(8):298-9   [PMID:  15275328 ]

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