| Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences. | |
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MedLine Citation:
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PMID: 19913304 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-gamma) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-gamma ELISAs. These are relevant in blood-based diagnosis of bovine tuberculosis, an important threat to lions in the Kruger National Park. Alignment of nucleotide and amino acid sequences of lion and cheetah and that of domestic cats showed homologies of 97-100%. |
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Authors:
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Miriam Maas; Ildiko Van Rhijn; Maria T E P Allsopp; Victor P M G Rutten |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-10-12 |
Journal Detail:
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Title: Veterinary immunology and immunopathology Volume: 134 ISSN: 1873-2534 ISO Abbreviation: Vet. Immunol. Immunopathol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8002006 Medline TA: Vet Immunol Immunopathol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 296-8 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. M.Maas3@students.uu.nl |
| Data Bank Information | |
Bank Name/Acc. No.:
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GENBANK/FJ712034; FJ712035; FJ712036; FJ712037 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acinonyx
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genetics*,
immunology* Amino Acid Sequence Animals Antibodies, Monoclonal / biosynthesis Base Sequence Cats Cattle Cloning, Molecular DNA Primers / genetics Enzyme-Linked Immunosorbent Assay / veterinary Interferon-gamma / genetics* Lions / genetics*, immunology* Molecular Sequence Data Sequence Homology, Amino Acid South Africa Species Specificity Tuberculosis, Bovine / diagnosis, transmission |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/DNA Primers; 82115-62-6/Interferon-gamma |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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