Document Detail

Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2.
MedLine Citation:
PMID:  19782019     Owner:  NLM     Status:  MEDLINE    
In a recent issue of Molecular Cell, Schulze et al. (2009) described distinct distributions and regulation of Dot1-dependent methylation states at lysine 79 on histone H3 and showed cell-cycle regulation of K79 dimethylation on genes expressed during the G1/S phase.
Jane Mellor
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Molecular cell     Volume:  35     ISSN:  1097-4164     ISO Abbreviation:  Mol. Cell     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-28     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802571     Medline TA:  Mol Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  729-30     Citation Subset:  IM    
Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
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MeSH Terms
Cell Cycle* / genetics
DNA, Intergenic
G1 Phase
Gene Expression Regulation, Fungal
Histone-Lysine N-Methyltransferase / genetics,  metabolism*
Histones / genetics,  metabolism*
Nuclear Proteins / genetics,  metabolism*
Nucleosomes / metabolism*
Open Reading Frames
Promoter Regions, Genetic
Protein Processing, Post-Translational*
S Phase
Saccharomyces cerevisiae / genetics,  growth & development,  metabolism*
Saccharomyces cerevisiae Proteins / genetics,  metabolism*
Reg. No./Substance:
0/DNA, Intergenic; 0/Histones; 0/Nuclear Proteins; 0/Nucleosomes; 0/Saccharomyces cerevisiae Proteins; 56-87-1/Lysine; EC protein, S cerevisiae; EC N-Methyltransferase
Comment On:
Mol Cell. 2009 Sep 11;35(5):626-41   [PMID:  19682934 ]

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