| Linkage analysis of the murine mos proto-oncogene on chromosome 4. | |
| | |
MedLine Citation:
|
PMID: 2568329 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A linkage analysis of the murine Mos gene, which codes for the c-mos proto-oncogene, was performed in 88 backcross progeny of an interspecies cross of laboratory mice and Mus spretus. Linkage was tested for four different genes on mouse chromosome 4: Aco-1, Mup-1, b, and Ifb. The gene order (from centromere) with intervening percentage recombination is Mos-15.9 (+/- 3.9)-Aco-1-5.6 (+/- 2.4)-Mup-1-3.4 (+/- 1.9)-b-5.6 (+/- 2.4)-Ifb. These results confirm the previous assignment of Mos to chromosome 4 on the basis of segregation in somatic cell hybrids (D. Swan et al., 1982, J. Virol. 44: 752-754) and show furthermore that Mos and the Ifa/Ifb clusters are not tightly linked as a group of intronless genes, but are separated by a map distance of 30.6 +/- 4.9 recombination units. The linkage data obtained in the present study place Mos in a region compatible with the physical map (D. W. Threadgill and J. E. Womack, 1988, Genomics 3: 82-86). |
| | |
Authors:
|
F Dandoy; J De Maeyer-Guignard; E De Maeyer |
Related Documents
:
|
9775349 - Genetics of alpha-amylases in hexaploid oat species. 1671809 - Linkage disequilibrium and modification of risk for huntington disease. 12778899 - Linkage: from particulate to interactive genetics. 10582279 - Report of the international equine gene mapping workshop: male linkage map. 8161019 - Assignment of the gene for porcine insulin-like growth factor 1 (igf1) to chromosome 5 ... 11811149 - Linkage analysis of three candidate regions of chromosome 1 in nonsyndromic familial or... 9605969 - Early stages of spindle formation and independence of chromosome and microtubule cycles... 9460799 - Angelman syndrome caused by loss of a marker chromosome: cytogenetic and fluorescence i... 291939 - Assignment of the gene for cytoplasmic superoxide dismutase (sod-1) to a region of chro... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Genomics Volume: 4 ISSN: 0888-7543 ISO Abbreviation: Genomics Publication Date: 1989 May |
Date Detail:
|
Created Date: 1989-08-22 Completed Date: 1989-08-22 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 8800135 Medline TA: Genomics Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 546-51 Citation Subset: IM |
Affiliation:
|
CNRS URA 1343, Institut Curie-Biologie, Centre Universitaire, Orsay, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aconitate Hydratase
/
genetics Animals Chromosome Mapping Female Genes Interferon Type I / genetics Linkage (Genetics) Male Mice / genetics* Mice, Inbred DBA / genetics Polymorphism, Restriction Fragment Length Proteins / genetics Proto-Oncogene Proteins / genetics* Proto-Oncogene Proteins c-mos Proto-Oncogenes* |
| Chemical | |
Reg. No./Substance:
|
0/Interferon Type I; 0/Proteins; 0/Proto-Oncogene Proteins; 0/major urinary proteins; EC 2.7.11.1/Proto-Oncogene Proteins c-mos; EC 4.2.1.3/Aconitate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Norrie disease: linkage analysis using a 4.2-kb RFLP detected by a human ornithine aminotransferase ...
Next Document: A genetic linkage map of 17 markers on human chromosome 21.