Document Detail


Correlation of particular bacterial PCR-denaturing gradient gel electrophoresis patterns with bovine ruminal fermentation parameters and feed efficiency traits.
MedLine Citation:
PMID:  20709849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of rumen microbial structure and functions on host physiology remains poorly understood. This study aimed to investigate the interaction between the ruminal microflora and the host by correlating bacterial diversity with fermentation measurements and feed efficiency traits, including dry matter intake, feed conversion ratio, average daily gain, and residual feed intake, using culture-independent methods. Universal bacterial partial 16S rRNA gene products were amplified from ruminal fluid collected from 58 steers raised under a low-energy diet and were subjected to PCR-denaturing gradient gel electrophoresis (DGGE) analysis. Multivariate statistical analysis was used to relate specific PCR-DGGE bands to various feed efficiency traits and metabolites. Analysis of volatile fatty acid profiles showed that butyrate was positively correlated with daily dry matter intake (P < 0.05) and tended to have higher concentration in inefficient animals (P = 0.10), while isovalerate was associated with residual feed intake (P < 0.05). Our results suggest that particular bacteria and their metabolism in the rumen may contribute to differences in host feed efficiency under a low-energy diet. This is the first study correlating PCR-DGGE bands representing specific bacteria to metabolites in the bovine rumen and to host feed efficiency traits.
Authors:
Emma Hernandez-Sanabria; Le Luo Guan; Laksiri A Goonewardene; Meiju Li; Denis F Mujibi; Paul Stothard; Stephen S Moore; Monica C Leon-Quintero
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-13
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  76     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2011-01-06     Revised Date:  2011-07-27    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6338-50     Citation Subset:  IM    
Affiliation:
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada.
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MeSH Terms
Descriptor/Qualifier:
Animal Feed*
Animals
Bacteria / classification*,  genetics*,  metabolism
Biodiversity*
Cattle / microbiology*
DNA, Bacterial / genetics
DNA, Ribosomal / genetics
Denaturing Gradient Gel Electrophoresis / methods
Diet
Fatty Acids / analysis
Fermentation
Male
Metagenome*
Polymerase Chain Reaction / methods
RNA, Ribosomal, 16S / genetics
Rumen / chemistry,  microbiology*
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/DNA, Ribosomal; 0/Fatty Acids; 0/RNA, Ribosomal, 16S
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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