Document Detail

Lingual subgemmal neurogenous plaques with pseudoepitheliomatous hyperplasia: incidental pseudomalignant condition.
MedLine Citation:
PMID:  16872442     Owner:  NLM     Status:  MEDLINE    
Pseudoepitheliomatous hyperplasia is a reactive proliferation of benign squamous epithelium that can mimic squamous cell carcinoma. Herein is a report on this type of reaction on two subgemmal neurogenous plaques in a lingual circumvallate papilla. To the authors' knowledge this is the first report on this combination of lesions. A 66-year-old man died with disseminated squamous cell carcinoma of the lung. At autopsy the tongue was found to have an incidental pseudoepitheliomatous hyperplasia on two subgemmal neurogenous plaques with ganglion cells. Subgemmal neurogenous plaque should be included in the differential diagnosis of causes of lingual pseudoepitheliomatous hyperplasia. Awareness of the morphological spectrum of subgemmal neurogenous plaques can avoid the overdiagnosis of these lesions as neural tumors or squamous cell carcinoma.
J Fernando Val-Bernal; Isidro Rivadulla; M Francisca Garijo
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology international     Volume:  56     ISSN:  1320-5463     ISO Abbreviation:  Pathol. Int.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-28     Completed Date:  2006-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9431380     Medline TA:  Pathol Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  462-5     Citation Subset:  IM    
Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain.
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MeSH Terms
Biological Markers / metabolism
Carcinoma, Squamous Cell / diagnosis,  secondary
Diagnosis, Differential
Epithelium / metabolism,  pathology*
Fatal Outcome
Hyperplasia / pathology
Lung Neoplasms / diagnosis,  pathology
Taste Buds / metabolism,  pathology*
Tongue / innervation,  metabolism,  pathology*
Tongue Diseases / metabolism,  pathology*
Tongue Neoplasms / diagnosis
Reg. No./Substance:
0/Biological Markers

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