Document Detail

Lingual squamous cell carcinoma in a California sea lion (Zalophus californianus).
MedLine Citation:
PMID:  12564535     Owner:  NLM     Status:  MEDLINE    
A 28-yr-old female California sea lion (Zalophus californianus) in a commercial aquarium developed an ulcerated lingual tumor and died. Necropsy revealed a moderately differentiated squamous cell carcinoma. Immunohistochemical staining and electron microscopic studies revealed that the tumor cells were strongly positive with anti-keratin-cytokeratin antibody and had abundant tonofibrils and desmosomes. The neoplasm had metastasized to a mandibular lymph node.
Tsuneo Sato; Tomomi Higuchi; Hisashi Shibuya; Shigeo Ohba; Sadao Nogami; Wataru Shirai; Hideaki Watanabe; Shigeaki Honda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  33     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2003-02-04     Completed Date:  2003-07-01     Revised Date:  2004-11-18    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  367-70     Citation Subset:  IM    
Laboratory of Veterinary Pathology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan.
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MeSH Terms
Animals, Zoo
Carcinoma, Squamous Cell / pathology,  veterinary*
Fatal Outcome
Immunohistochemistry / veterinary
Lymphatic Metastasis
Sea Lions*
Tongue Neoplasms / pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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