Document Detail

Linear scleroderma: a response to neurologic injury? Report and literature review.
MedLine Citation:
PMID:  2685298     Owner:  NLM     Status:  MEDLINE    
A 28-year-old white man presented with neurologic symptoms and skin changes. Subsequent evaluation led to the diagnosis of transverse myelitis of the cervical spine (C8) and linear scleroderma. The progression of neurologic abnormalities prompted treatment with corticosteroids. Neurologic symptoms diminished and the progression of linear skin lesions halted. A review of the literature uncovered considerable evidence for underlying abnormalities of the spine and spinal cord in many patents with linear scleroderma and a paucity of immunologic abnormalities characteristic of progressive systemic sclerosis. Patients presenting with new onset linear scleroderma should be evaluated for underlying neurologic causes.
B H Littman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  16     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1990-01-11     Completed Date:  1990-01-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1135-40     Citation Subset:  IM    
Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond.
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MeSH Terms
Muscle Hypotonia / etiology
Myelitis, Transverse / complications*,  drug therapy
Prednisone / therapeutic use
Scleroderma, Localized / drug therapy,  etiology*,  pathology
Reg. No./Substance:

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